Benzoxazine compounds and pharmaceutical use thereof

Details Benzoxazine compounds and pharmaceutical use thereof Benzoxazine compounds and pharmaceutical use thereof

1988-10-24

1990-01-09

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544105, A61K 31535, C07D26536

Patent

active

048928720

ABSTRACT:
Benzoxazine compounds of the formula: ##STR1## wherein each symbol is as defined in the specification. The compounds exhibit 5-HT.sub.3 receptor antagonistic activity so that they are useful as antiemetics and so on.

REFERENCES:
The Lancet, Jun. 27, 1987, pp. 1470-1472.
Nature, vol. 316; Jul. 11, 1985, Richardson et al., pp. 126-131.

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