Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-11-07
1997-12-09
Datlow, Philip I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544105, 549313, A61K 31535, C07D26536, C07D41310, C07D41312
Patent
active
056961170
ABSTRACT:
The invention relates to benzoxazine and pyrido-oxazine antibacterial compounds of the general formula: ##STR1## wherein the moiety Q is a fused phenyl or fused pyridyl moiety as herein described, pharmaceutical compositions containing the compounds, methods for their production and their use in treating bacterial infections.
REFERENCES:
Kumonaka et al Chemical Abstract 121:280655j (1994).
Masuoka et al, Chem. Pharm. Bull 34(1), pp. 130-139 (1986).
McOmie, "Protecting Groups in organic Chemistry", Plenum Press, (1973), pp. 95, & 119-120.
Greene, "Protective Groups in Organic Synthesis", John Wiley & Sons, (1981), pp. 10-12.
M. J. Mahan, J. M. Slauch and J. J. Mekalanos, Science, 259, 686-688 (1993).
S. Roychoudhury et al., Proc. Nat. Acad. Sci., 90, 965-969 (1993) Inhibitors of Two-Component Signal Transduction Systems: Inhibition of Alginate Gene Activation in Pseudomonas Aeruginosa.
International Search Report--International Application No. PCT/US96/16669--International Filing Date Oct. 17, 1996.
Chemical Abstracts, vol. 82, No. 23, Jun. 9, 1975 No. 150506(b), p. 141, Takami.
Chemical Abstracts, vol. 105, No. 21, 24 Nov. 1986, No. 191020(a) p. 723, Mourin.
Chemical Abstracts, vol. 107, No. 17, 29 Oct., 1987, No. 154344(e) p. 704, Shridhar.
Chemical Abstracts, vol. 108, No. 25, 20 Jun. 1988, No. 221648(t) p. 569, Sastry.
Chemical Abstracts, vol. 114, No. 7, 17 Feb., 1991, No. 62024(s) p. 683, Jayamma.
Frechette Roger
Weidner-Wells Michele Ann
Datlow Philip I.
Dow Kenneth J.
Ortho Pharmaceutical Corporation
LandOfFree
Benzoxazine antimicrobial agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzoxazine antimicrobial agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzoxazine antimicrobial agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1607874