Benzoxazine antimicrobial agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544105, A61K 31535, C07D26536

Patent

active

058542426

ABSTRACT:
The invention relates to benzoxazine and pyrido-oxazine antibacterial compounds of the general formula: ##STR1## wherein the moiety Q is a fused phenyl or fused pyridyl moiety as herein described, pharmaceutical compositions containing the compounds, methods for their production and their use in treating bacterial infections.

REFERENCES:
patent: 3635956 (1972-01-01), Krapcho
patent: 3725403 (1973-04-01), Krapcho
International Search Report application number PCT/US96/19627 filed 11 Dec. 1996.
Chem. Pharm. Bull. (CPBTAL. 00092363);86; vol. 34 (1); pp. 130-139, Takeda Chem. Ind., Ltd; Cent. Res.Div; Osaka; 532; japan (JP) XP002030883 Syntheses of 3,4-Dihydro-2H-1,4-Benzoxazine-2-Acetates and Related Compounds, 1986.
Chem Abstract, vol. 124, No. 9 26 Feb. 1997, Columbus, Ohio US; Abstract No. 117209, Jayamma Y et al; "Synthesis and Biological Evaluation of diazoles" XP0002030884.
Chem Abstract Bol. 123, No. 21, 20 Nov. 1995, Columbus, Ohio, US; Abstract No. 285925, Jayamma Y et al; "Synthesis and Biological Activities of Pyrazoles and 3-Methylpyrazoliones" XP002030885.

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