Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1989-09-29
1990-12-11
Gerstl, Robert
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C07D49804
Patent
active
049772589
ABSTRACT:
Compounds of formula III: ##STR1## wherein R.sup.1 is a 5- or 6-membered aromatic heterocyclic group; and R.sup.4 and R.sup.5 each idependently signify hydrogen, halogen, trifluoromethyl, cyano, nitro, amino or lower alkyl; are useful intermediates in a novel process for the preparation of a class of pharmacologically active compounds of formula I: ##STR2## wherein R.sup.1, R.sup.4 and R.sup.5 are as defined above; and R.sup.3 represents hydrogen or lower alkyl.
REFERENCES:
patent: 4622320 (1986-11-01), Ferrosan
patent: 4622321 (1986-11-01), Ferrosan
patent: 4880799 (1989-11-01), Watger
Houghton Peter G.
Wright Stanley H. B.
DiPrima Joseph F.
Gerstl Robert
Merck Sharp & Dohme Ltd.
Polk Manfred
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