Benzothiophene derivatives and antihyperuricemia thereof

Details Benzothiophene derivatives and antihyperuricemia thereof Benzothiophene derivatives and antihyperuricemia thereof

1992-04-17

1992-12-29

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514382, 514469, 549 57, 549 58, 549462, 549467, A61K 3138

Patent

active

051751844

ABSTRACT:
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic adic derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.

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patent: 5004750 (1991-02-01), Tomiyama et al.
patent: 5118707 (1992-06-01), Chatterjee et al.

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