Benzothiophene, benzofuran and indole-thiazepinones, oxazepinone

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514220, 540488, 540495, A61K 3155, C07D51304

Patent

active

055654460

ABSTRACT:
Benzothiophene, benzofuran and indolethiazepinones, oxazepinones and diazepinones as well as methods of preparation thereof are described as agents which inhibit leukocyte adherence to vascular endothelium and, as such, are effective therapeutic agents for treating inflammatory diseases; these compounds also inhibit the activation of human immunodeficiency virus (HIV).

REFERENCES:
patent: 4013641 (1977-03-01), Brown
PCT Search Report, PCT/US 95/01275.
Chemical Abstracts, vol. 105, No. 25, 1986, abstract No. 226266q, Nagarajan et al.
Chemical Abstracts, vol. 115, No. 21, 1991, abstract No. 232194n, Hiremath et al.
Chemical Abstracts, vol. 89, No. 5, 1978, abstract No. 43178u, Glushkov et al.
International Preliminary Examination Report, PCT/US 94/01275.

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