Benzothiophene analogs as antiviral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5462811, C07D40906, A61K 3144

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active

057475113

ABSTRACT:
Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R.sup.1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.

REFERENCES:
patent: 3933827 (1976-01-01), Brossi et al.
patent: 4018780 (1977-04-01), Lappi et al.
patent: 4045565 (1977-08-01), Le Pecq et al.
patent: 4310667 (1982-01-01), Le Pecq et al.
patent: 4334070 (1982-06-01), Berger et al.
patent: 4483989 (1984-11-01), Le Pecq et al.
patent: 4851417 (1989-07-01), Archer
patent: 4897398 (1990-01-01), Gros et al.
Cheng et al. (1983) "Unique spectrum of activity of and its mode of action against herpes simplex virus type 1" Proc. Natl. Acad. Sci. USA 80:2767-2770.
Duke et al. (1986) "In vitro and in vivo activities of phosphate derivatives of 9-(1,3-dihydroxy-2-propoxymethyl guanine against cytomegaloviruses" Antiviral Research 6:299-308.
Shafiee et al. CA 84(25):180104C, 1976.

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