Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-02-21
1997-02-04
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544 49, 544 33, 514 64, 514 81, 5142245, A61K 3154, C07D27902
Patent
active
055998119
ABSTRACT:
Novel benzothiazine dioxides which are antagonists of endothelin are described, as well as novel intermediates used in their preparation, methods for the preparation, and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, essential renovascular malignant and pulmonary hypertension, cerebral infarction, cerebral ischemia, congestive heart failure, and subarachnoid hemorrhage.
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Berryman Kent A.
Bunker Amy M.
Doherty Annette M.
Edmunds Jeremy J.
Anderson Elizabeth M.
Ford John M.
Warner-Lambert & Company
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