Benzoquinolizines and hypotensive compositions containing them

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260283SA, 260283S, 260287CF, 260288CF, 260289C, A61K 3147, C07D45506

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active

040768201

ABSTRACT:
The invention relates to novel benzoquinolizines of the general formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein R.sup.1 and R.sup.2 which may be the same or different, each represent hydrogen, lower alkyl, lower alkoxy or halogen, R.sup.3 represents hydrogen, lower alkyl or aryl and R.sup.4 represents --SO.sub.2 R.sup.5 (where R.sup.5 is lower alkyl or aryl, --CONH.sub.2 or --CXNHR.sup.6 (where X is oxygen or sulphur and R.sup.6 is aryl or aryl.CO.--). The compounds have hypotensive activity.

REFERENCES:
patent: 3634431 (1972-01-01), Van Dyke, Jr.
patent: 3652570 (1972-03-01), Gittos et al.
patent: 3995041 (1976-11-01), Havera et al.

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