Benzopyranyltetrazoles as antiasthma agents

Details Benzopyranyltetrazoles as antiasthma agents Benzopyranyltetrazoles as antiasthma agents

1975-01-03

1977-12-20

Rush, Raymond V.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

A61K 3141

Patent

active

040642569

ABSTRACT:
There are described compounds of formula I, ##STR1## in which R.sub.5, R.sub.6, R.sub.7 and R.sub.8, which may be the same or different, are hydrogen, alkyl C2 to 6, alkoxy C2 to 8, hydroxy-alkoxy C3 to 8, and R.sub.5 may be hydroxy, provided that one or two of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are other than hydrogen, and pharmaceutically acceptable derivatives thereof. The compounds of formula I are indicated for use in the treatment of asthma, and pharmaceutical compositions containing them and processes for their preparation are also described.

REFERENCES:
patent: 3427324 (1969-02-01), Fitzmaurice
patent: 3706768 (1972-12-01), Bays
patent: 3839339 (1974-10-01), Ellis et al.
Buchanan et al., J. Med. Chem., vol. 12, pp. 1001-1006 (1969).
Juby et al., I, J. Med. Chem., vol. 11, pp. 111-117 (1968).
Juby et al., II, J. Med. Chem., vol. 12, pp. 396-401 (1969).

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