Benzopyrano[3,4-d]pyridine-2-cyano, carboxamidoximes and carboxi

Details Benzopyrano[3,4-d]pyridine-2-cyano, carboxamidoximes and carboxi Benzopyrano[3,4-d]pyridine-2-cyano, carboxamidoximes and carboxi

1976-11-08

1978-06-20

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260296H, C07D49104, A61K 3144

Patent

active

040962652

ABSTRACT:
Benzopyrano[3,4-d]pyridine-2-cyano, carboxamidoximes and carboximidates of the formula ##STR1## wherein R represents -C.ident.N, ##STR2## R.sub.1 is a lower alkyl, R.sub.2 is hydrogen or a lower alkyl and R.sub.3 is a straight or branched alkyl having 1 to 20 carbons, a cycloalkyl-lower alkyl group in which the cycloalkyl group has 3 to 8 carbons or it is an arylalkyl group, and R.sub.4 is a lower alkyl group.
The compounds are useful for lowering blood pressure.

REFERENCES:
patent: 3535327 (1970-10-01), Pars et al.
International Union of Pure and Applied Chemistry, Nomenclature of Organic Chemistry, Definitive Rules for Section A, Hydrocarbons Section B, Fundamental Heterocyclic Systems etc. pp. 25-26, London, Butterworths Scientific Publications, 1958.
Patterson et al., The Ring Index 2nd ed. pp. 1271-1272, American Chemical Society, 1960.
Chemical Abstracts, Eighth Collective Index, vols. 66-75, 1967-1971, Subjects Benzimidazolin-By p. 4369S.
Harris et al., Chem. Abst. 1973, vol. 79, No. 92191v.
Harris et al., Chem. Abst., 1974, vol. 80, No. 63863f.
Pars et al., J. Amer. Chem. Soc., 1966, vol. 88, pp. 3664-3665.
Sterling Drug Chem. Abst., 1970, vol. 72, 66922v.

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