Benzopyran derivatives having inhibitory activities against...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C549S404000

Reexamination Certificate

active

08048912

ABSTRACT:
The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-β receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.

REFERENCES:
patent: 4681890 (1987-07-01), Kanehira et al.
patent: 5703075 (1997-12-01), Gammill et al.
patent: 5763470 (1998-06-01), Tang et al.
patent: 6492390 (2002-12-01), Carter et al.

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