Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-03-19
1999-11-09
Kunz, Gary L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514455, 514457, 549282, 549285, 536 8, A61K 3170, A61K 3137, A61K 3135, C07D31108
Patent
active
059814950
ABSTRACT:
The present invention offers a safe and effective drug for heart diseases and a safe and effective method for treating heart diseases such as ischemic heart disease and cardiac arrhythmia. The method comprises administering a pathologically effective amount of a benzopyran derivative expressed by the following general formula (I): ##STR1## wherein R.sup.1 is an alkyl group or an alkenyl group, R.sup.2 is a hydrogen atom, an alkyl group, an alkyl group having at least one hydroxyl group, an alkenyl group, an acyl group or a glycosyl group; or physiologically acceptable salts thereof.
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Witiak et al., Synthetic Aci-Reductones: 3,4-Dihydroxy2-H-I-benzopyran-2-ones and Their cis-and trans-4a,5,6,7,8,8a-Hexahydro Diastereomers. Antiaggregatory, Antilipidemic, and Redox Properties Compared to Those of the 4-Substituted 2-Hydroxytetronic Acids, J. Med. Chem. 1988, vol. 31, pp. 1437-1445.
Abe Masayoshi
Aoki Yasuo
Kimura Nobuyuki
Misumi Osamu
Nakanishi Shigenori
Dainippon Ink and Chemicals Inc.
Kunz Gary L.
White Everett
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