Benzopyran compounds

Details Benzopyran compounds Benzopyran compounds

1992-05-01

1994-05-24

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546146, 546159, 546256, A61K 3135, A61K 3144, A61K 3147, C07D 3104, C07D40512

Patent

active

053150171

ABSTRACT:
A compound selected from the group consisting of those of formula I ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, X and n are defined in the description, an optical isomer thereof, and an addition salt thereof with a pharmaceutically-acceptable base or acid.
Medicinal product which is useful in treating or in preventing a disorder due to or linked to the phenomena of peroxidation and to the disturbance of the eicosanoid biosynthesis.

REFERENCES:
patent: 4816484 (1989-03-01), Toyoshima et al.
patent: 5017604 (1991-05-01), Belliotti et al.
Davies, Kelvin J. A., "Oxidative Damage and Repair, Chemical, Biological and Medical Aspects", Pergamon Press, page xxi, 1990.
Halliwell, Barry, "Drug Antioxidant Effects-A Basis for Drug Selection", USA in Drugs 42 (4), 569-605 (1991).
Slater, T., and Jacob, H. S., "New Developments In Free Radical Research", International Conference held Oct. 15-16, 1990.
Goodman and Gilman, "The Pharmacological Basis of Therapeutics", 8th Edition, Pergamon Press, p. 603 (1983).
Goodman and Gilman, "The Pharmacological Basis of Therapeutics", 8th Edition, Pergamon Press, pp. 600, 610 (1983).

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