Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-08-26
1976-01-06
Davis, C.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260562, C07C10334
Patent
active
039313140
ABSTRACT:
The present invention relates to pharmacologically valuable new benzophenone derivatives having a pronounced sedative action on the central nervous system and some of which also possess muscle-relaxing and aggression-inhibiting properties. These new derivatives have the structural formula ##EQU1## and their acid addition salts, in which R.sub.1 and R.sub.2 are substituents selected from the group consisting of hydrogen, saturated and unsaturated alkyl groups having 1-4 carbon atoms; R.sub.3 is a substituent selected from the group consisting of --CN, --CONH.sub.2, --COOCH.sub.3, --COOC.sub.2 H.sub.5, --COOH, and --COOMe, where Me is a metallic cation; n is an integer selected from 1 and 2; and m is an integer selected from 1,2, and 3, and wherein the rings A and B may be substituted, ring A being substituted preferably with a halogen such as chlorine or with nitro, trifluoromethyl, methyl, methoxy or methylmercapto, preferably in the 5 position, and ring B being preferably substituted in the 2' position with chlorine or fluorine. The radicals R.sub.1 and R.sub.2 preferably signify hydrogen or a methyl group, or a n-butyl group in the case of Ring B.
REFERENCES:
patent: 3334100 (1967-09-01), Zenitz
patent: 3429874 (1969-02-01), Topliss
patent: 3729470 (1973-04-01), Vaille
Greve Heinz Gunter
Resag Klaus
Cassella Farbwerke Mainkur Aktiengesellschaft
Crawford Francis M.
Davis C.
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