Benzophenone derivatives

Details Benzophenone derivatives Benzophenone derivatives

1974-11-22

1977-01-25

Killos, Paul J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268R, 26029374, 26032647, 260471C, 424263, 42424854, 424309, C07D 9500

Patent

active

040050858

ABSTRACT:
Benzophenone derivatives are produced which have the formula ##STR1## wherein R.sub.1 signifies hydrogen, nitro, halogen or trifluoromethyl; R.sub.2 represents hydrogen or halogen; R.sub.3, R.sub.4 and R.sub.5 are the same or different and signify hydrogen or lower alkyl; R.sub.6 and R.sub.7 each represent lower alkyl or together with the nitrogen atom form a morpholino, 4-(lower alkyl)-1-piperazinyl, 1-pyrrolidinyl or piperidino group, A signifies an alkylene group with 2 to 8 C atoms and Y represents oxygen or a group ##STR2## R.sub.8 and R.sub.9 each signifying lower alkyl or together signifying lower alkylene.
The benzophenone derivatives and their pharmaceutically acceptable salts exhibit sedative, anti-convulsant, muscle relaxant and anxiolytic activities.
Also provided are methods for the preparation of these compounds.

REFERENCES:
patent: 3100222 (1963-08-01), Beaver
patent: 3160648 (1964-12-01), O'Brochta et al.
patent: 3927010 (1975-12-01), Hellerbach et al.

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