Benzoic acid derivatives as non nucleoside...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C564S181000, C564S184000, C514S563000, C514S621000

Reexamination Certificate

active

07569723

ABSTRACT:
Compounds of formula (I):wherein R1, R2, R3, R4, R5and R6are as defined herein. The compounds are useful as reverse transcriptase inhibitors against HIV. In particular, the compounds are active against wild type and single or double mutant strains of HIV.

REFERENCES:
patent: 2004/0122064 (2004-06-01), Chan
patent: 2383782 (2001-03-01), None
patent: 1438973 (2004-07-01), None
patent: 0117982 (2001-03-01), None
patent: 0196338 (2001-12-01), None
patent: 02070470 (2002-09-01), None
patent: 03075907 (2003-09-01), None
patent: 2004009533 (2004-01-01), None
patent: 2004050643 (2004-06-01), None
Berge, et al; Pharmaceutical Salts; Journal of Pharmaceutical Science; Jan. 1977; vol. 66; No. 1; pp. 1-19.
Wyatt, et al: Benzophenone Derivatives: A Novel Series of Potent and Selective Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase; J. Med. Chem.; 1995; vol. 38; pp. 1657-1665; American Chemical Society.
Chan, et al; Novel Benzophenones as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1; J. Med. Chem.; 2004; vol. 47; pp. 1175-1182; American Chemical Society.
Nader, et al; Synthesis of [carbonyl-11C]2-(2-benzoylphenoxy)-N-phenylacetamide from [11C]carbon monoxide by the Suzuki and the Stille reactions; Applied Radiation and Isotopes; 2002; vol. 57; pp. 681-685; Pergamon.
Balzarini, J.; Current Status of the Non-nucleoside Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Type 1; Current Topics in Medicinal Chemistry; May 2004; vol. 4(9); pp. 921-944.
De Clercq; The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection; Antiviral Research; 1998; vol. 38; pp. 153-179.
Pauwels; new non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections; Current Opinion in Pharmacology, Web Release: Aug. 24, 2004; pp. 437-446.
Pedersen, et al; Non-nucleoside reverse transcriptase inhibitors: the NNRTI boom; Antiviral Chemistry & Chemotherapy; 1999; vol. 10; pp. 285-314.
Andries, et al; TMC125, a novel next generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1; Antimicrobial Agents & Chemotherapy; Dec. 2004; vol. 48 (12); pp. 4680-4686.

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