Benzoic acid derivative and benzenesulfonic acid mucolytic proce

Details Benzoic acid derivative and benzenesulfonic acid mucolytic proce Benzoic acid derivative and benzenesulfonic acid mucolytic proce

1978-03-24

1979-01-02

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31255

Patent

active

041328027

ABSTRACT:
A mucolytic process is disclosed which comprises contacting N-(2-hydroxyethyl)mercaptoacetamidobenzamides or mercaptoacylamidobenzoic acids, mercaptoacetylsulfanilic acids and alkanoylthio derivatives thereof with mucus. Illustrative of compounds useful in the mucolytic process of the present invention are 4-(2-mercaptoacetamido)benzoic acid and N-(2-mercaptoacetyl)sulfanilic acid.

REFERENCES:
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patent: 2520293 (1950-08-01), Weiss
patent: 2607789 (1952-08-01), Weiss
patent: 3091569 (1963-05-01), Sheffner
patent: 3663690 (1972-05-01), Eichel et al.
patent: 3770824 (1973-11-01), Phillips et al.
patent: 3809697 (1971-10-01), Martin et al.
A. L. Sheffner, Ann. New York Acad. Sci., 106, 298-310, (1963).
N. S. Poonia et al., Indian J. Appl. Chem. 27(1) 32-33 (1964).

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