Benzoguanamine derivatives, their production and pharmaceutical

Details Benzoguanamine derivatives, their production and pharmaceutical Benzoguanamine derivatives, their production and pharmaceutical

1981-05-22

1982-06-08

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544207, C07D25148, C07D40112, A61K 3144, A61K 3153

Patent

active

043339336

ABSTRACT:
Novel 2-amino-4-nicotinoylamino-6-halogenophenyl-s-triazines and acid addition salts thereof, possessing strong anti-inflammatory action when the phenyl group is mono- or di-halogen substituted. The compounds are formulated into pharmaceutical compositions in bulk or dosage form, and are administered to humans and animals having inflammatory conditions or disorders until the same are reduced or overcome. The novel compounds are prepared by various procedures such as reacting a benzoguanamine which is halogen-substituted with an active derivative of nicotinic acid, and recovering the 2-amino-4-nicotinoylamino-6-halogenophenyl-s-triazines thus formed.

REFERENCES:
patent: 4291162 (1981-09-01), Matsumura et al.

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