Benzofuran inhibitors of factor VIIa

Details Benzofuran inhibitors of factor VIIa Benzofuran inhibitors of factor VIIa

2007-09-25

2007-09-25

Owens, Amelia A. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S470000, C549S466000, C549S467000

Reexamination Certificate

active

10850231

ABSTRACT:
Compounds of Formula I are useful for inhibiting serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein and have improved pharmacokinetic properties. These compounds may be used in methods of preventing and/or treating clotting disorders.

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