Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-07-28
1989-01-10
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548252, 549 58, 549446, 549447, A61K 3134, C07D30780
Patent
active
047974150
ABSTRACT:
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.
REFERENCES:
patent: 3920707 (1975-11-01), Descamps et al.
patent: 3947470 (1976-05-01), Brenner et al.
patent: 3963758 (1976-06-01), Pinhas et al.
patent: 4163794 (1979-08-01), Cragoe et al.
patent: 4255585 (1981-03-01), Thuillier nee Nachmias et al.
Kubota Koichi
Tomiyama Akira
Tomiyama Tsuyoshi
Burns Robert E.
Kotobuki Seiyaku Company Limited
Lobato Emmanuel J.
Raymond Richard L.
Springer W. B.
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