Benzofuran compounds and their use

Details Benzofuran compounds and their use Benzofuran compounds and their use

1996-03-14

1998-03-03

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514374, 514376, 548183, 548226, 548235, C07D41712, A61K 3140

Patent

active

057234795

ABSTRACT:
Benzofuran compound represented by the formula: ##STR1## wherein ##STR2## represents a group capable of releasing a cation in which ....... represents a single or double bond: R.sup.1 represents an optionally substituted heterocyclic residue which may be attached to the oxygen atom through a carbon chain; R.sup.2 represents a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon residue, an optionally protected hydroxyl group or an optionally protected amino group; Y represents a di- or tri-valent aliphatic hydrocarbon residue having 1 to 8 carbon atoms; and the benzene ring of the benzofuran moiety may have further substituents; or a salt thereof, which has excellent hypoglycemic and hypolipidemic action.

REFERENCES:
patent: 4455427 (1984-06-01), Johnson, II
patent: 4495357 (1985-01-01), Johnson
patent: 4738972 (1988-04-01), Essler
patent: 5401761 (1995-03-01), Goldstein
Dow et al., Journal of Medicinal Chemistry, vol. 34, pp. 1538-1544 (1991).

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