Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-05-20
1999-07-20
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514256, 514337, 514422, 514469, 544212, 544328, 544329, 5462841, 548525, 549462, 549468, 549471, C07D30783, C07D40112, A61K 3134
Patent
active
059256362
ABSTRACT:
Compounds having the formula (i), ##STR1## wherein the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined herein. The compounds of the present invention can be utilized to treat disease states capable of being modulated by inhibition of proteins which mediate cellular activity, such as tumor necrosis factor (TNF) and/or phosphodiesterase IV (PDE IV).
REFERENCES:
Damasio, Alzheimer's Disease and related dementias, Cecil Textbook of Medicine, 20th Edition, vol. 2, pp. 1992-1996, 1996.
Christensen et al., Chem. Abstract 76:99520, 1972.
Dyke Hazel Joan
Lowe Christopher
Montana John Gary
Darwin Discovery Limited
Rao Deepak R.
Shah Mukund J.
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