Benzofuran and benzothoiphene derivatives, of tetrazole and anti

Details Benzofuran and benzothoiphene derivatives, of tetrazole and anti Benzofuran and benzothoiphene derivatives, of tetrazole and anti

1988-12-06

1991-04-02

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548253, C07D40712, C07D40912, A61K 3138, A61K 3141

Patent

active

050047507

ABSTRACT:
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.

REFERENCES:
patent: 4085219 (1978-04-01), Cragoe et al.
patent: 4107172 (1978-08-01), Biel et al.

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