Benzofuran and benzothiophene derivatives, anti-hyperuricemia ag

Details Benzofuran and benzothiophene derivatives, anti-hyperuricemia ag Benzofuran and benzothiophene derivatives, anti-hyperuricemia ag

1992-04-21

1993-12-28

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549468, C07D30787, A61K 3134

Patent

active

052740005

ABSTRACT:
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.

REFERENCES:
patent: 3920707 (1975-11-01), Descamps et al.
patent: 3963758 (1976-06-01), Pinhas et al.
patent: 4179515 (1979-12-01), Mieville
patent: 4207341 (1980-06-01), Hubner
patent: 4565828 (1986-01-01), Descamps et al.

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