Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-04-21
1993-12-28
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549468, C07D30787, A61K 3134
Patent
active
052740005
ABSTRACT:
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.
REFERENCES:
patent: 3920707 (1975-11-01), Descamps et al.
patent: 3963758 (1976-06-01), Pinhas et al.
patent: 4179515 (1979-12-01), Mieville
patent: 4207341 (1980-06-01), Hubner
patent: 4565828 (1986-01-01), Descamps et al.
Kubota Koichi
Tomiyama Akira
Tomiyama Tsuyoshi
Burns Robert E.
Kotobuki Seiyaku Company Limited
Lobato Emmanuel J.
Springer David B.
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