Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-03-26
1977-03-01
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260268TR, 260268BC, C07D29508
Patent
active
040102670
ABSTRACT:
Benzodioxole compounds of the formula: vasodilator ##STR1## WHEREIN R.sub.1 is hydrogen, lower alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl,
R.sub.2 is lower-alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl, or
R.sub.1 + r.sub.2 are --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.5 -- or --(CH.sub.2).sub.6 -- and
Het is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, quinazolinyl, 1,3,5 triazinyl or 1,3-thiazolyl, each being optionally substituted by lower-alkyl, lower-alkoxy, hydroxyl or phenyl.
These compounds are used as medicines especially as peripheral vasocilator agent and central nervous system stimulant.
REFERENCES:
patent: 3299067 (1967-01-01), Regnier et al.
patent: 3585193 (1971-06-01), Regnier et al.
Canevari Roger
Laubie Michel
Poignant Jean-Claude
Regnier Gilbert
Coughlan, Jr. Paul M.
Hueschen Gordon W.
Science Union et Cie Societe Francaise de Recherche Medical
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