Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-07-06
1980-02-05
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602393P, 544290, C07D47104
Patent
active
041873068
ABSTRACT:
The invention covers compounds of the formula ##STR1## in which R.sup.1 and R.sup.5 each represents 0, 1, 2, 3 or 4 of the following substituents: alkyl, hydroxyl, acyloxy, alkoxy, nitro, amino, alkylamino, dialkylamino, acylamino, acylalkylamino, alkoxycarbonylamino, halogen, trifluoromethyl, cyano, carboxyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminosulphonyl, alkylaminosulphonyl, dialkylaminoamino, R.sup.2 is hydrogen, optionally substituted alkyl, aralkyl or aryl or heterocyclo-alkyl, acyl or alkoxycarbonyl, and R.sup.3 and R.sup.4 are each hydrogen, or optionally substituted alkyl, aralkyl, aryl or hetero-aryl, are useful as medicaments which have an action on the central nervous system, in particular as, for example, tranquilizers and/or antiamnesics. Also included in the invention are methods for preparing said compounds, compositions containing them and methods for the use of said compounds and compositions.
REFERENCES:
patent: 3651046 (1972-03-01), Derieg et al.
Harrison et al., "J. Heterocyclic Chemistry", vol. 14, No. 7, pp. 1191-1196 (1977), (Nov.).
Chemical Abstracts, vol. 88, Item 105281n, abstracting Harrison et al., in "J. Heterocyclic Chemistry", (1977), vol. 14, No. 7, pp. 1191-1196 (English).
Heise Arend
Heitzer Helmut
Hoffmeister Friedrich
Kazda Stanislav
Mayer Karl H.
Bayer Aktiengesellschaft
Bond Robert T.
Rotman Alan L.
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