Benzodiazepine derivatives as APP modulators

Details Benzodiazepine derivatives as APP modulators Benzodiazepine derivatives as APP modulators

2006-09-12

2006-09-12

Kfle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S221000, C540S506000, C540S509000, C540S562000, C540S572000

Reexamination Certificate

active

07105509

ABSTRACT:
A novel class of 1,4- and 1,5-benzodiazepines of formula (I) is disclosed. The compounds modulate the processing of amyloid precursor protein by γ-secretase, and hence find use in the treatment or prevention of conditions associated with the deposition of β-amyloid, such as Alzheimer's disease

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