Benzodiazepine carboxamides and pharmaceutical compositions with

Details Benzodiazepine carboxamides and pharmaceutical compositions with Benzodiazepine carboxamides and pharmaceutical compositions with

1975-04-30

1977-09-20

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260295A, 2602433, 42424854, 42424853, A61K 3144, C07D22316

Patent

active

040498123

ABSTRACT:
There is disclosed a novel heterocyclic compound of the general formula: ##STR1## wherein each of R.sup.1 and R.sup.2 represents hydrogen atom, or an alkyl group which may be substituted by alkyl-substituted amino, hydroxy or alkoxy group, or R.sup.1 and R.sup.2 may form a heterocyclic ring together with the nitrogen atom adjacent thereto; R.sup.3 represents hydrogen atom or a lower alkyl group; P.sub.y represents a pyridyl group; B represents a lower alkylene group which may have lower alkyl group as a substituent; Y represents oxygen atom, sulfur atom or --NH-- group; and ring A is either unsubstituted or substituted by halogen atom, nitro, lower alkyl, lower alkoxy or polyhalo-lower alkyl group. This class of compounds is found to be useful as medicine in human and animal therapy, which act on the central nervous system, for example, muscle relaxants, anticonvulsants, sedatives, minor tranquilizers. There is also disclosed intermediates for the production of said compound.

REFERENCES:
patent: 3767661 (1973-10-01), Hester, Jr.
patent: 3870714 (1975-03-01), Gagneux et al.
patent: 3905956 (1975-09-01), Derieg et al.
patent: 3914215 (1975-10-01), Tachikawa et al.

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