Benzodiazepine antagonistic .beta.-carboline derivatives and com

Details Benzodiazepine antagonistic .beta.-carboline derivatives and com Benzodiazepine antagonistic .beta.-carboline derivatives and com

1984-06-22

1986-07-15

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514234, 514236, 514292, 544 60, 544126, 544361, 546 85, 546 87, A61K 3168, A61K 31535, C07D47106, C07D40306

Patent

active

046007156

ABSTRACT:
.beta.-carboline derivatives of general Formula I ##STR1## wherein R.sup.3 is ##STR2## wherein R.sup.5 is C.sub.1-5 alkyl, R.sup.6 is lower alkyl, aralkyl, or alkoxyalkyl of up to 7 carbon atoms, and R.sup.7 and R.sup.8 are hydrogen C.sub.1-5 alkyl, or, collectively with the amido nitrogen atom, piperidino,

REFERENCES:
patent: 4371536 (1983-02-01), Braestrup et al.
patent: 4435403 (1984-03-01), Braestrup et al.
Neef et al., CA 99 (1983), p. 742.

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