Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-09-23
1978-07-04
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424244, A61K 3155, C07D24316
Patent
active
040987868
ABSTRACT:
1,4-benzodiazepin of the formula ##STR1## wherein R is a low molecular straight or branched alkyl and X is halogen or trifluoromethyl, and pharmaceutically acceptable acid addition salts of these benzodiazepins. The benzodiazepins are made by heating an acyldiamine in the presence of phosphorus oxychloride at the latter's boiling point followed by reacting the resulting mixture of 7-member and 8-member compounds with an alkali metal alkoxide.
REFERENCES:
patent: 3723414 (1973-03-01), Steinman
Hoffman La Roche, Chem. Abst., vol. 65, col. 15407-15408 (1966).
Budden Renke
Funke Siegfried
Huschens Rolf
Liepmann Hans-Gunther
Milkowski Wolfgang
Daus Donald G.
Kali-Chemie Aktiengesellschaft
Springer W. B.
Striker Michael J.
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