Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-12-14
1993-10-12
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514422, 5142315, 546206, 548527, 544146, A61K 3138, A61K 31445
Patent
active
052525899
ABSTRACT:
There is disclosed a benzocycloheptene compound of the formula: ##STR1## wherein R.sup.1 is hydrogen atom, a halogen atom or a lower alkoxy group, R.sup.2 and R.sup.3 are independently selected from hydrogen atom, a lower alkyl group and a lower alkenyl group, or R.sup.2 and R.sup.3 combine together with adjacent nitrogen atom to form a heteromonocyclic group, or a pharmaceutically acceptable salt thereof, which has an excellent inhibitory activity against contraction of urinary bladder.
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Chemical Abstracts, vol. 62, 11751b (1965).
Thies et al., J. Org. Chem., vol. 45, pp. 185-187 (1980).
Wong et al., J. Med. Chem. vol. 27, pp. 20-27 (1984).
Jones et al., J. Chem. Soc., (C), pp. 2176-2181 (1969).
Ishizuka Tohru
Morimoto Masamichi
Nosaka Kunio
Ozeki Masakatsu
Yasuda Kosuke
Cintins Marianne M.
Peabody John
Tanabe Seikayu Co., Ltd.
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