Benzobicycloalkane derivatives as anticonvulsant neuroprotective

Details Benzobicycloalkane derivatives as anticonvulsant neuroprotective Benzobicycloalkane derivatives as anticonvulsant neuroprotective

1989-05-04

1990-05-08

Siegel, Alan

Music

549 74, 549 76, 549 77, 549492, 549494, 549495, C07D33312, C07D33322, C07D30702

Patent

active

049240080

ABSTRACT:
The use of the compounds: ##STR1## where R is hydrogen, alkyl, alkoxy, hydroxy, alkanoyloxy, phenylalkoxy, halo or trifluoromethyl; R.sup.1 is alkyl, alkenyl or phenylalkyl; R.sup.2 is hydrogen, alkyl, phenylalkyl, alkenyl, alkynyl, thienylalkyl or furylalkyl; n is one of the integers 2, 3, 4, 5 or 6; or a pharmaceutically acceptable salt thereof, as NMDA antagonists in the treatment of convulsions and neurodegenerative disease states. The compounds in which R.sup.2 are heterocyclylalkylamines are novel and useful NMDA antagonists.

REFERENCES:
patent: 4001331 (1977-01-01), Freed et al.
J. Med. Chem. 16, 595, (1973).
J. Med. Chem. 19, 476, (1976).
J. Med. Chem. 19, 560, (1976).

Affiliated with

Also associated with

Rating

Benzobicycloalkane derivatives as anticonvulsant neuroprotective does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzobicycloalkane derivatives as anticonvulsant neuroprotective, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzobicycloalkane derivatives as anticonvulsant neuroprotective will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2350211