Benzoamide piperidine containing compounds and related...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C546S113000, C546S018000, C514S256000, C514S322000, C514S278000, C544S333000

Reexamination Certificate

active

07119207

ABSTRACT:
The present invention relates to certain benzoamide piperidine containing compounds and related compounds that exhibit activity as NK-1 receptor antagonists, (e.g., substance P receptor antagonists), to pharmaceutical compositions containing them, and to their use in the treatment and prevention of central nervous system disorders, inflammatory disorders, cardiovascular disorders, ophthalmic disorders, gastrointestinal disorders, disorders caused byhelicobacter pylori, disorders of the immune system, urinary incontinence, pain, migraine, emesis, angiogenesis and other disorders.

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Cordero, et al.; Syntheses of 3-Phenyl Substituted Idolizidin-2-ones and a Pyrrolizidin-2-one on the Route to Constrained Potential NK1Receptor Antagonists; Tetrahedron; vol. 50, No. 44 pp. 12713-12726 (1994).

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