Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1993-11-02
1995-08-01
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
A61K 31395, C07D51306, C07D49806, C07D48706
Patent
active
054381363
ABSTRACT:
There are disclosed certain novel compounds identified as benzo-fused macrocycles which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused macrocycles as the active ingredient thereof are also disclosed.
REFERENCES:
patent: 3239345 (1966-03-01), Hodge et al.
patent: 4036979 (1977-07-01), Asato
patent: 4411890 (1983-10-01), Momany
Jones, et al J. Chem. Soc. pp. 2176-2181 (1969).
Davis, et al. Arch. Biochem. Biophys 102, pp. 48-51 (1963).
Wattley, et al J. Med. Chem. 28. pp. 1511-1516 (1985).
Slade, et al. J. Med. Chem 28, pp. 1517-1521 (1985).
Ott. Arch. Pharm. (Weinheim. Gen) 325 (9) pp. 601-603 (1990).
Huang, et al. Synthesis 10 p. 851 (1984).
Stewart, Autralia J. Chem. 33 pp. 633-640 (1980).
Still, et al J. Org. Chem. 43 p. 2923 (1978).
Devita Robert J.
Frontier Alison J.
Schoen William R.
Wyvratt, Jr. Matthew J.
Bond Robert T.
Merck & Co. , Inc.
Rose David L.
Thies J. Eric
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