Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-

Details Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2- Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-

1989-12-21

1991-04-23

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514429, 546112, 548465, 548517, 548525, 548526, A31K 3140, C07D22122, C07D40104, C07D40304

Patent

active

050100858

ABSTRACT:
Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetrahy dronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.

REFERENCES:
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4115435 (1978-09-01), O'Brien et al.
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lenicer et al.
patent: 4359476 (1982-11-01), Kaplan et al.
patent: 4360531 (1982-11-01), McMillan et al.
patent: 4438130 (1984-03-01), Kaplan
patent: 4460600 (1984-07-01), Kaplan
patent: 4466977 (1984-08-01), McMillan et al.
patent: 4499286 (1985-02-01), Binder
patent: 4632935 (1986-12-01), Kaplan
patent: 4656182 (1987-04-01), Horwell
patent: 4663343 (1987-05-01), Horwell et al.
patent: 4735959 (1988-04-01), Grell
Martin, Pharmacol. Rev., vol. 19, pp. 463-521, (1967).
Martin, Pharmacol. Exp. Ther., vol. 197, pp. 517-532, (1976).
Von Voigtlander et al., J. Pharmacol. Exp. Ther., vol. 224, pp. 7-12, (1983).
Medicinal Chemistry, Burger (ed.), p. 42, (1960).

Affiliated with

Also associated with

Rating

Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2- will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1621565