Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,

Details Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1, Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,

1989-12-21

1991-08-27

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514429, 514454, 514455, 548525, 549389, A61K 3140, A61K 3135, C07D40504, C07D31192

Patent

active

050433504

ABSTRACT:
Benzo-fused cycloalkane and oxa- and thia- cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetra hydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.

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