Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-12-26
1991-06-25
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514249, 544344, 544354, A61K 31495, C07D24138, C07D24144
Patent
active
050267043
ABSTRACT:
Heterocyclic dihydroxyquinoxaline compounds having the formula ##STR1## wherein R.sup.1 is C.sub.1-12 -alkyl, which may optionally be substututed by hydroxy, formyl, carboxy, carboxylic esters, amides or amines, C.sub.3-8 -cycloalkyl, aryl, aralkyl; and wherein R.sup.6 is, hydrogen, halogen, CN, CF.sub.3, NO.sub.2, or OR', wherein R' is C.sub.1-4 -alkyl and R.sup.5, R.sup.7 and R.sup.8 is hydrogen, provided R.sup.6 is not CF.sub.3, OCH.sub.3, NO.sub.2, Cl or Br when R.sup.1 is CH.sub.3 ; or
REFERENCES:
patent: 3431111 (1969-03-01), Brooker et al.
patent: 4889855 (1989-12-01), Jacobsen et al.
patent: 4912108 (1990-03-01), Jacobsen et al.
patent: 4948794 (1990-08-01), Honore et al.
Jacobsen et al., Chemical Abstracts, vol. 110, No. 75568 (1989) (Abstract for EP283959).
Yamatani et al., Chemical Abstracts, vol. 73, No. 131029 and 131031 (1970).
Honore Tage
Jacobsen Poul
Naerum Lars
Nielsen Flemming E.
Bernhardt F.
Hueschen Gordon W.
Novo Nordisk A S
Shen Cecilia
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