Benzo[f]quinoline intermediates

Details Benzo[f]quinoline intermediates Benzo[f]quinoline intermediates

1987-11-18

1988-06-07

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540461, 540463, C07D22106

Patent

active

047497912

ABSTRACT:
Benzazecinediones of the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen or chlorine, R.sup.3 is hydrogen, fluorine, chlorine, bromine or methoxy, R.sup.4 is hydrogen, chlorine or methoxy and R.sup.5 is hydrogen, acetyl, propionyl, benzoyl, chlorobenzoyl, methoxybenzoyl or phenylacetyl, with the proviso that 2 or 3 of the groups R.sup.1 to R.sup.4 are hydrogen,
as well as many of the corresponding benzo[f]quinolines from which these benzazecinediones can be prepared by oxidation are suitable for the control or prevention of cerebral insufficiency or for the improvement of cognitive functions in mammals. They can be produced according to various processes and can be prepared into pharmaceutical compositions.

REFERENCES:
patent: 2313138 (1943-03-01), Frohlich et al.
patent: 4341786 (1982-07-01), DeMarinis et al.
patent: 4521423 (1985-06-01), Asselin et al.

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