Benzo[b ]pyrano[3,2- h ]acridin-7-one cinnamate compounds

Details Benzo[b ]pyrano[3,2- h ]acridin-7-one cinnamate compounds Benzo[b ]pyrano[3,2- h ]acridin-7-one cinnamate compounds

2006-12-05

2006-12-05

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S047000

Reexamination Certificate

active

07144891

ABSTRACT:
A compound selected from those of formula (I):wherein:X and Y represent a group selected from hydrogen, halogen, alkoxy, nitro, cyano, alkyl, alkenyl, polyhaloalkyl and —NRaRbwherein Raand Rbare as defined in the description,Z represents oxygen or NRcwherein Rcis as defined in the description,Ar represents aryl or heteroaryl,R1represents hydrogen or alkyl,R2represents a group selected from hydrogen, alkyl, —ORaand —NRaRbwherein Raand Rbare as defined in the description,R3and R4represent hydrogen or alkyl,R5represents hydrogen, ORc, NRcRd, W1—C(W2)—U—V, W1—C(W2)—W3-T1or Z-CO—CH═CHAr wherein Rc, Rd, W1, W2, W3, U, V, T, Z and Ar are as defined in the description,its isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.

REFERENCES:
patent: 6503919 (2003-01-01), Koch et al.

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