Benzo[B]Furancarboxamide derivatives, process for the preparatio

Details Benzo[B]Furancarboxamide derivatives, process for the preparatio Benzo[B]Furancarboxamide derivatives, process for the preparatio

1994-08-04

1995-08-15

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514414, C07D48704, A61K 3140

Patent

active

054420776

ABSTRACT:
There are disclosed a benzo[b]furancarboxamide derivative of the formula ##STR1## wherein R.sup.a, R.sup.b, R.sup.c and R.sup.d are a hydrogen atom or lower alkyl group, respectively; R.sup.e is a hydrogen atom, amino radical, lower alkylamino group or acylamino group; X is a hydrogen atom or halogen atom; and n is an integer of 1-5,
and including racemic compounds and stereo-isomers thereof, a salt of the compounds, a process for the preparation of the compounds and salts as well as use thereof for improving hypermotility.

REFERENCES:
Naunyn-Schmiedeberg's Arch. Pharmacol., vol. 343, p. 439 (1991).
"Abstract of the 98th Annual Lecture Meeting in the Pharmacological Society of Japan", p. 223 (1978).
Bulletin of Pharmacological Society of Japan, vol. 92, p. 297 (1988).
The Merck Index, 10th ed., p. 6063.
J. Med. Chem., vol. 34, p. 616 (1991).

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