Benzo[A]phenothiazines and hydro-derivatives

Details Benzo[A]phenothiazines and hydro-derivatives Benzo[A]phenothiazines and hydro-derivatives

1985-03-28

1986-09-09

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 99, C07D26538, C07D27920, C07D27930

Patent

active

046110569

ABSTRACT:
Pharmaceutical compositions containing a compound of Formula I: ##STR1## wherein X is O, S, SO or SO.sub.2 and R.sub.2, R.sub.3, R.sub.4 and R.sub.5 may be positioned anywhere on the structure, or a pharmaceutically-acceptable salt thereof and certain novel benzo[a]phenothiazines, which compositions and compounds are useful in treating allergic conditions, asthma, cardiovascular disorders, inflammation and pain and are useful as cytoprotective agents.

REFERENCES:
patent: 3580947 (1971-05-01), Ikeda et al.
J. Inst. Chem. (India) 49, 286-287, 1977, (Mital et al.).
J. Org. Chem. 32, 1190-1194, 1967, (Jackson et al.).
J. Org. Chem. 34, 1691-1694, 1969, (VanAllan et al.).
J. Med. Chem. 11, 622-623, 1968, (Jackson et al.).
Acta Chim. Acad. Sci. Hung. 92, 89-97, 1977, (Agarwal et al.).
Anorg. Chem. Org. Chem. 33B, 214-215, 1978, (Tiwari et al.).
Indian J. Chem. Sect. B, 17B, 408-409, 1979, (Tiwari et al.).
J. Het. Chem. 19, 167-169, 1982, (Ueno et al.).
Morrison et al., Organic Chemistry, 1966, Allyn & Bacon, Inc., Boston, pp. 96-101 & 282-290.

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