Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546 93, A61K 3144, A61K 31445, C07D40104, C07D40304

Patent

active

058520341

ABSTRACT:
Compounds of the following formula useful for inhibiting Ras function and therefore inhibiting or treating the abnormal growth of cells are disclosed: ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein: R and R.sup.2 are halo;

REFERENCES:
patent: 5151423 (1992-09-01), Piwinski et al.
patent: 5661152 (1997-08-01), Bishop et al.
patent: 5714609 (1998-02-01), Doll et al.
patent: 5719148 (1998-03-01), Bishop et al.

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