Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as

Details Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as

1998-09-29

2000-03-21

Huang, Evelyn Mei

Textiles: spinning, twisting, and twining

574256, 574290, 544316, 544318, 546 93, A61K 31445, A61K 31505, C07D23904, C07D40114, C07D40314

Patent

active

060396830

ABSTRACT:
Compounds of the following formula useful for inhibiting Ras function and therefore inhibiting or treating the abnormal growth of cells are disclosed: ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein: R and R.sup.2 are halo;

REFERENCES:
patent: 5151423 (1992-09-01), Piwinski et al.
patent: 5661152 (1997-08-01), Bishop et al.
patent: 5714609 (1998-02-01), Doll et al.
patent: 5719148 (1998-02-01), Bishop et al.
Khosravi-Far R. et al. Cell Growth & Differentiation. 3, 461-469, Jul. 1992 .

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