Benzo[1,8]naphthyridine derivatives as antimicrobials

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 14, 546 81, A01N 4342

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active

049905155

ABSTRACT:
New benzo[b][1,8]naphthyridine derivatives of general formula (I), in which R is a hydrogen atom or an alkyl, fluoroalkyl, cycloalkyl (3 to 6 C), alkoxy or alkylamino radical or an amine protective radical and either Hal is a fluorine, chlorine or bromine atom and R' is a hydrogen atom or Hal and R' are simultaneously fluorine atoms, their salts, their preparation and the compositions which contain them.
These new products can be used as antimicrobial agents for topical application or as synthesis intermediates. ##STR1##

REFERENCES:
patent: 4133885 (1979-01-01), Bolhofer et al.
patent: 4169893 (1979-10-01), Hardtmann
patent: 4229456 (1980-10-01), Bolhofer et al.
Chem Abstracts, vol. 61, 10666g, (1964).

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