Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1984-02-27
1984-12-25
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548241, 549258, 549268, 424285, C07D26120, C07D26100, A61K 3142, A61K 3134
Patent
active
044903847
ABSTRACT:
Described are compounds of the formula ##STR1## wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula ##STR2## wherein X' and Y' may be the same or different and are selected from hydrogen, loweralkyl, or halo, and Z' is hydrogen, loweralkyl, halo, hydroxy or loweralkoxy, or pharmaceutically acceptable salts thereof.
The compounds possess diuretic activity.
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Zergenyi, et al., "Indole-and benzofuran-2-carboxylic acids" Chem. Abst. 71:91282y (1969).
Libis, et al., ". . . diuretic 5-acyl-2,3-dihydrobenzo[.beta.]-furan carboxylic acids", Chem. Abst. 72:43426x (1970).
Zergenyi et al., "5-benzofuran-2-carboxylic acids," Chem. Abst. 75:35697h (1971).
Fanelli, et al., "Diuretic . . . benzofuran-2-carboxylic acid . . . , " Chem. Abst. 92:104364n (1980).
Fung Anthony K.
Plattner Jacob J.
Abbott Laboratories
Daus Donald G.
Hendricks G.
Katz M. L.
Weinstock S. F.
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