Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-18
2007-12-18
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S304400, C548S304700, C548S310100, C548S310400
Reexamination Certificate
active
10977609
ABSTRACT:
The present invention relates to compounds of Formula I:or a pharmaceutically acceptable salt thereof, wherein the R1, Z, Y, RA, and W groups of formula I are as defined herein. The invention also provides pharmaceutically acceptable compositions and methods of using the compositions in the treatment of various disorders.
REFERENCES:
patent: 3162644 (1964-12-01), Englisch et al.
patent: 4088768 (1978-05-01), Paget et al.
patent: 2005/0113283 (2005-05-01), Solow-Cordero et al.
patent: 0563001 (1993-09-01), None
patent: WO 00/59886 (2000-10-01), None
patent: WO 00/78728 (2000-12-01), None
patent: WO 01/32174 (2001-05-01), None
patent: WO 01/96289 (2001-12-01), None
patent: WO 03/062392 (2003-07-01), None
Maekawa et al, “Pesticides derived from amino acids,” Chemical Abstracts Services, (1984), Database accession No. BRN: 1976:554963.
Walter et al, “Preparatio of 2-(alpha-aminoalkyl)benzimifsxoles,” Chemical Abstracts Services, (1060), Database Accession No. 1960:80598.
Balboni et al., “Evaluation of Dmt-Tci Pharmacophore: Conversion of a Potent Opioid Receptor Antagonist into a Potenbt Agonist and Ligands with Mixed Properties,” Journal of Medicinal Chemistry 45(3):713-720 (2002).
Rangarajan et al, “2″-substituted 5-phenylterbenzimidazoles as topoisomerase I poisons”, Bioorganic & Medicinal Chemistry, 8:1371-1382 (2000).
Database Crossfire Beilstein, Collect. Czech. Chem, Commun. 15:196-200 (1950), Database Accession No. 231224.
Database Crossfire Beilstein, Tetrahedron Letters, 43(16):3003-3006 (2002), Database Accession No. 287207.
Database Crossfire Beilstein, J. Indian Chem. Soc., 53:310-311 (1976), Database Accession No. 924836.
Database Crossfire Beilstein, Indian J. Chem. Sect. A., 15:568 (1977), Database Accession No. 291714.
Database Crossfire Beilstein, Chem. Pharm. Bull., 12:127-129 (1964), Database Accession No. 547537.
Database Crossfire Beilstein, Indian J. Chem. Sect. B., 26:73-74 (1987), Database Accession No. 223899.
Database Crossfire Beilstein, Journal of Medicinal Chemistry, 40(15):22890-2292 (1997), Database Accession No. 7782964.
Database Crossfire Beilstein, Chemical and Pharmaceutical Bulletin, 34(6):2501-2505 (1986), Database Accession No. 5579945.
Database Crossfire Beilstein Mutat. Res. 467(1):41-54 (2000), Database Accession No. 8485329.
Database Crossfire Beilstein, Chem. Heterocycl. Compd., 5:649-650 (1969), Database Accession No. 921882.
Database Crossfire Beilstein, Eur. J. Med. Chem. Chim. Ther., 14:435-438 (1979), Database Accession No. 917933.
Fanning Lev T. D.
Gonzalez, III Jesus E.
Termin Andreas P.
Wilson Dean M.
Zhang Yulian
Anderson Rebecca
Badia Michael C.
Chu Yong
Vertex Pharmaceuticals Incorporated
LandOfFree
Benzimidazoles useful as modulators of ion channels does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzimidazoles useful as modulators of ion channels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzimidazoles useful as modulators of ion channels will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3862762