Benzimidazoles for the treatment of atherosclerosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514394, A61K 31415

Patent

active

052908011

ABSTRACT:
This invention relates to imidazoles, namely, fused-ring heterocycles as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT), pharmaceutical compositions containing them, processes for their preparation, and their use as antihypercholesterolemic and/or antiatherosclerotic agents for the treatment of atherosclerosis.

REFERENCES:
patent: 3718662 (1973-02-01), Venkatachala et al.
patent: 4814329 (1989-03-01), Harsanyi et al.
patent: 5179115 (1993-01-01), Bruneau et al.

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