Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-05-29
1994-03-01
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514394, A61K 31415
Patent
active
052908011
ABSTRACT:
This invention relates to imidazoles, namely, fused-ring heterocycles as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT), pharmaceutical compositions containing them, processes for their preparation, and their use as antihypercholesterolemic and/or antiatherosclerotic agents for the treatment of atherosclerosis.
REFERENCES:
patent: 3718662 (1973-02-01), Venkatachala et al.
patent: 4814329 (1989-03-01), Harsanyi et al.
patent: 5179115 (1993-01-01), Bruneau et al.
Higley C. Anne
Muduskuie, Jr. Thomas P.
Wexler Ruth R.
Wilde Richard G.
Fato Gildo E.
Gabilan Mary Susan H.
Lee Mary C.
The Du Pont Merck Pharmaceutical Company
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