Benzimidazoles and benzothiazoles as inhibitors of map kinase

Details Benzimidazoles and benzothiazoles as inhibitors of map kinase Benzimidazoles and benzothiazoles as inhibitors of map kinase

2008-01-22

2008-01-22

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S394000, C548S152000, C548S235000, C548S255000, C548S302100, C548S315100, C548S343500, C548S364700, C548S366100, C548S373100, C548S379400

Reexamination Certificate

active

10522227

ABSTRACT:
The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis

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