Benzimidazole derivatives, process for the preparation thereof a

Details Benzimidazole derivatives, process for the preparation thereof a Benzimidazole derivatives, process for the preparation thereof a

1982-10-22

1984-02-07

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424273R, 2602456, 544370, A61K 31495, A61K 3155, C07D40302

Patent

active

044303432

ABSTRACT:
Novel benzimidazole derivatives of the formula: ##STR1## wherein R.sup.1 is an alkyl group having 1 to 3 carbon atoms, allyl group, propargyl group, or phenyl group; R.sup.2 is hydrogen atom or an alkyl group having 1 to 3 carbon atoms; and n is 2 or 3, or pharmaceutically acceptable acid addition salts thereof, which have excellent antihistaminic activities and are useful as antiallergics for various allergic diseases, and a process for the preparation thereof, and an antihistaminic composition containing the compound as an active ingredient.

REFERENCES:
patent: 2689853 (1954-09-01), Schenck et al.
patent: 3423413 (1969-01-01), Priewe et al.
patent: 4093726 (1978-06-01), Winn et al.

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